25B-NBF

Description

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25I-NBF (2C-I-NBF, Cimbi-21, NBF-2C-I) Get 25B-NBF research chemicals online. It is derived from the phenethylamine hallucinogen 2C-I, which binds to the human 5-HT2A receptor very strongly. It has been investigated in its 11C radiolabelled form as a possible ligand for positron emission tomography (PET) imaging of the location of 5-HT2A receptors in the brain.

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Phenethylamine hallucinogen 2C-I has an N-benzyl derivative called 25I-NBF, 25b-nboh, 25b-nbome, which is a very strong partial agonist for the 5-HT2A receptor.

25b NBF Powder For Sale 

As a novel psychoactive compound, 25B-NBF, also known as 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-fluorobenzyl) ethanamine, falls under the phenethylamine category. It has been identified as a potent agonist of the 5-hydroxytryptamine receptor. While its metabolic and elimination processes are not fully understood, extensive research using liquid chromatography–high-resolution mass spectrometry has been conducted on its properties in human hepatocytes, human cDNA-expressed cytochrome P450 (CYP), and UDP-glucuronosyltransferase (UGT) enzymes. This research aims to aid in the detection of 25b nboh misuse. 

After being incubated with a mixture of human hepatocytes, 25B-NBF underwent considerable metabolization into 33 metabolites: hydroxylation, O-demethylation, bis-O-demethylation, N-debenzylation, glucuronidation, sulfation, and acetylation. The hepatic extraction ratio for this process was 0.80. The enzymes CYP1A1, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2J2, CYP3A4, and UGT2B7 catalyzed the metabolism of 25b-nbome and Methamphetamine. These findings indicate that in order to screen for 25B-NBF abuse, a bioanalytical approach for determining both 25B-NBF and its metabolites in biological samples must be developed. 

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It’s similar to 2C-B

IUPAC name: 2-(4-bromo-2,5-Dimethoxyphenyl)-N-(2-fluorobenzyl) ethanamine

Formula: C17H19BrFNO2

Purity: 99,7% min

Appearance: white powder

This product is NOT for human consumption.